> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > GNAQ Antibody (N-term)Brand |
Leading Biology | Catalog Number |
APR03922G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GNAQ Antibody (N-term).
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Molecular Weight |
42142 Da
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Cellular Localization |
Antigen Cellular Localization:
Nucleus. Membrane. Nucleus membrane. Note=Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
52-78 aa
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Target |
This GNAQ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-78 amino acids from the N-terminal region of human GNAQ.
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Isotype |
Rabbit Ig
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Symbol |
GAQ
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GeneID |
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UniProt ID |
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Function |
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity).
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Summary |
This locus encodes a guanine nucleotide-binding protein.The encoded protein, an alpha subunit in the Gq class, couples aseven-transmembrane domain receptor to activation of phospolipaseC-beta. Mutations at this locus have been associated with problemsin platelet activation and aggregation. A related pseudogene existson chromosome 2.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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