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UBP46 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR03920G 100 μl / $495

UBP46 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR03920G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality UBP46 Antibody (C-term).

Molecular Weight

42442 Da

Host

Rabbit

Species Reactivity

Human

Immunogen

241-269 aa

Target

This UBP46 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 241-269 amino acids from the C-terminal region of human UBP46.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Not involved in deubiquitination of monoubiquitinated FANCD2.

Summary

Modification of cellular proteins by ubiquitin is anessential regulatory mechanism controlled by the coordinated actionof multiple ubiquitin-conjugating and deubiquitinating enzymes.USP46 belongs to a large family of cysteine proteases that functionas deubiquitinating enzymes (Quesada et al., 2004 [PubMed14715245]).

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

UBP46 Antibody (C-term) (Cat. APR03920G) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the UBP46 antibody detected the UBP46 protein (arrow).

Specification

Quantity

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