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MYB Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR03896G 100 μl / $495

MYB Antibody (Center)

Brand

Leading Biology

Catalog Number

APR03896G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MYB Antibody (Center).

Molecular Weight

72341 Da

Cellular Localization

Antigen Cellular Localization: Nucleus {ECO:0000255|PROSITE- ProRule:PRU00625, ECO:0000269|PubMed:19646965}

Host

Rabbit

Species Reactivity

Human

Immunogen

419-448 aa

Target

This MYB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 419-448 amino acids from the Central region of human MYB.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.

Summary

This gene encodes a transcription factor that is a memberof the MYB family of transcription factor genes. The proteincontains three domains, an N-terminal DNA-binding domain, a centraltranscriptional activation domain and a C-terminal domain involvedin transcriptional repression. This protein plays an essential rolein the regulation of hematopoiesis and may play a role intumorigenesis. Alternative splicing results in multiple transcriptvariants.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Images

MYB Antibody (Center) (Cat. APR03896G) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the MYB antibody detected the MYB protein (arrow).

MYB Antibody (Center) (Cat. APR03896G)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MYB Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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