> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > CCR10 Antibody (N-term)Brand |
Leading Biology | Catalog Number |
APR03860G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CCR10 Antibody (N-term).
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Molecular Weight |
38416 Da
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Cellular Localization |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
1-30 aa
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Target |
This CCR10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CCR10.
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Isotype |
Rabbit Ig
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Symbol |
GPR2
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GeneID |
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UniProt ID |
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Function |
Receptor for chemokines SCYA27 and SCYA28. Subsequently transduces a signal by increasing the intracellular calcium ions level and stimulates chemotaxis in a pre-B cell line.
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Summary |
Chemokines are a group of small (approximately 8 to 14kD), mostly basic, structurally related molecules that regulatecell trafficking of various types of leukocytes throughinteractions with a subset of 7-transmembrane, G protein-coupledreceptors. Chemokines also play fundamental roles in thedevelopment, homeostasis, and function of the immune system, andthey have effects on cells of the central nervous system as well ason endothelial cells involved in angiogenesis or angiostasis.Chemokines are divided into 2 major subfamilies, CXC and CC, basedon the arrangement of the first 2 of the 4 conserved cysteineresidues; the 2 cysteines are separated by a single amino acid inCXC chemokines and are adjacent in CC chemokines. CCR10 is thereceptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactionsare involved in T cell-mediated skin inflammation (Homey et al.,2002 [PubMed 11821900]).
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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