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BTN3A1 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR03824G 100 μl / $495

BTN3A1 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR03824G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality BTN3A1 Antibody (C-term).

Molecular Weight

57677 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Single- pass type I membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

345-374 aa

Target

This BTN3A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 345-374 amino acids from the C-terminal region of human BTN3A1.

Isotype

Rabbit Ig

Symbol

BTF5

GeneID

UniProt ID

Function

Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.

Summary

The butyrophilin (BTN) genes are a group of majorhistocompatibility complex (MHC)-associated genes that encode typeI membrane proteins with 2 extracellular immunoglobulin (Ig)domains and an intracellular B30.2 (PRYSPRY) domain. Threesubfamilies of human BTN genes are located in the MHC class Iregion: the single-copy BTN1A1 gene (MIM 601610) and the BTN2(e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A1) genes, whichhave undergone tandem duplication, resulting in 3 copies of each(summary by Smith et al., 2010 [PubMed 20208008]).[supplied byOMIM].

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

BTN3A1 Antibody (C-term) (Cat. APR03824G) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the BTN3A1 antibody detected the BTN3A1 protein (arrow).

Specification

Quantity

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