> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > SGPP1 Antibody (N-term)Brand |
Leading Biology | Catalog Number |
APR03792G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SGPP1 Antibody (N-term).
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Molecular Weight |
49108 Da
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Cellular Localization |
Antigen Cellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
13-42 aa
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Target |
This SGPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human SGPP1.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Has enzymatic activity against both sphingosine 1- phosphate (S1P) and dihydro-S1P. Regulates intracellular and extracellular S1P levels.
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Summary |
Sphingosine-1-phosphate (S1P) is a bioactive sphingolipidmetabolite that regulates diverse biologic processes. SGPP1catalyzes the degradation of S1P via salvage and recycling ofsphingosine into long-chain ceramides (Mandala et al., 2000 [PubMed10859351]; Le Stunff et al., 2007 [PubMed 17895250]).[supplied byOMIM].
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
WB~~1:1000
IHC-P~~1:10~50
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Images |
Anti-SGPP1 Antibody (N-term) at 1:1000 dilution + human placenta lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 49 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
SGPP1 Antibody (N-term) (Cat. APR03792G) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the SGPP1 antibody detected the SGPP1 protein (arrow).
SGPP1 Antibody (N-term) (Cat. APR03792G)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SGPP1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
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Specification |
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Quantity |
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Tel: 1-661-524(LBI)-0262
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