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SGPP1 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR03792G 100 μl / $495

SGPP1 Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR03792G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SGPP1 Antibody (N-term).

Molecular Weight

49108 Da

Cellular Localization

Antigen Cellular Localization: Endoplasmic reticulum membrane; Multi-pass membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

13-42 aa

Target

This SGPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human SGPP1.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Has enzymatic activity against both sphingosine 1- phosphate (S1P) and dihydro-S1P. Regulates intracellular and extracellular S1P levels.

Summary

Sphingosine-1-phosphate (S1P) is a bioactive sphingolipidmetabolite that regulates diverse biologic processes. SGPP1catalyzes the degradation of S1P via salvage and recycling ofsphingosine into long-chain ceramides (Mandala et al., 2000 [PubMed10859351]; Le Stunff et al., 2007 [PubMed 17895250]).[supplied byOMIM].

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Images

Anti-SGPP1 Antibody (N-term) at 1:1000 dilution + human placenta lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 49 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

SGPP1 Antibody (N-term) (Cat. APR03792G) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the SGPP1 antibody detected the SGPP1 protein (arrow).

SGPP1 Antibody (N-term) (Cat. APR03792G)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SGPP1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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