> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > FCAR Antibody (Center)Brand |
Leading Biology | Catalog Number |
APR03756G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality FCAR Antibody (Center).
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Molecular Weight |
32265 Da
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Cellular Localization |
Antigen Cellular Localization:
Isoform A.1: Cell membrane; Single-pass type I membrane protein Isoform A.3: Cell membrane; Single-pass type I membrane protein Isoform B-delta-S2: Secreted.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
58-84 aa
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Target |
This FCAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-84 amino acids from the Central region of human FCAR.
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Isotype |
Rabbit Ig
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Symbol |
CD89
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GeneID |
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UniProt ID |
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Function |
Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production.
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Summary |
This gene is a member of the immunoglobulin genesuperfamily and encodes a receptor for the Fc region of IgA. Thereceptor is a transmembrane glycoprotein present on the surface ofmyeloid lineage cells such as neutrophils, monocytes, macrophages,and eosinophils, where it mediates immunologic responses topathogens. It interacts with IgA-opsonized targets and triggersseveral immunologic defense processes, including phagocytosis,antibody-dependent cell-mediated cytotoxicity, and stimulation ofthe release of inflammatory mediators. Multiple alternativelyspliced transcript variants encoding different isoforms have beendescribed for this gene.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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