> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > F2RL2 Antibody (N-term)Brand |
Leading Biology | Catalog Number |
APR03671G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality F2RL2 Antibody (N-term).
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Molecular Weight |
42508 Da
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Cellular Localization |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
21-50 aa
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Target |
This F2RL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human F2RL2.
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Isotype |
Rabbit Ig
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Symbol |
PAR3
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GeneID |
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UniProt ID |
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Function |
Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.
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Summary |
Coagulation factor II (thrombin) receptor-like 2 (F2RL2)is a member of the large family of 7-transmembrane-region receptorsthat couple to guanosine-nucleotide-binding proteins. F2RL2 is alsoa member of the protease-activated receptor family and activated bythrombin. F2RL2 is activated by proteolytic cleavage of itsextracellular amino terminus. The new amino terminus functions as atethered ligand and activates the receptor. F2RL2 is a cofactor forF2RL3 activation by thrombin. It mediates thrombin-triggeredphosphoinositide hydrolysis and is expressed in a variety oftissues.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
WB~~1:1000
IHC-P~~1:10~50
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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