> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > PRSS7 Antibody (C-term E979)Brand |
Leading Biology | Catalog Number |
APR03667G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PRSS7 Antibody (C-term E979).
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Molecular Weight |
112935 Da
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Cellular Localization |
Antigen Cellular Localization:
Membrane; Single-pass type II membrane protein
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
964-994 aa
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Target |
This PRSS7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 964-994 amino acids from the C-terminal region of human PRSS7.
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Isotype |
Rabbit Ig
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Symbol |
ENTK, PRSS7
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GeneID |
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UniProt ID |
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Function |
Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.
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Summary |
This gene encodes an enzyme that converts the pancreaticproenzyme trypsinogen to trypsin, which activates other proenzymesincluding chymotrypsinogen and procarboxypeptidases. The precursorprotein is cleaved into two chains that form a heterodimer linkedby a disulfide bond. This protein is a member of the trypsin familyof peptidases. Mutations in this gene cause enterokinasedeficiency, a malabsorption disorder characterized by diarrhea andfailure to thrive.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, FC, E
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Dilution |
WB~~1:1000
IHC-P~~1:10~50
FC~~1:10~50
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Images |
Anti-PRSS7 Antibody (E979) at 1:1000 dilution + A549 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 113 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
PRSS7 Antibody (C-term E979) (Cat. APR03667G)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PRSS7 Antibody (C-term E979) for immunohistochemistry. Clinical relevance has not been evaluated.
PRSS7 Antibody (C-term E979) (Cat. APR03667G) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis. |
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Specification |
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Quantity |
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2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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