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PRSS7 Antibody (C-term E979)

Catalog # Availability Size / Price Inquiry
APR03667G 100 μl / $495

PRSS7 Antibody (C-term E979)

Brand

Leading Biology

Catalog Number

APR03667G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PRSS7 Antibody (C-term E979).

Molecular Weight

112935 Da

Cellular Localization

Antigen Cellular Localization: Membrane; Single-pass type II membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

964-994 aa

Target

This PRSS7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 964-994 amino acids from the C-terminal region of human PRSS7.

Isotype

Rabbit Ig

Symbol

ENTK, PRSS7

GeneID

UniProt ID

Function

Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.

Summary

This gene encodes an enzyme that converts the pancreaticproenzyme trypsinogen to trypsin, which activates other proenzymesincluding chymotrypsinogen and procarboxypeptidases. The precursorprotein is cleaved into two chains that form a heterodimer linkedby a disulfide bond. This protein is a member of the trypsin familyof peptidases. Mutations in this gene cause enterokinasedeficiency, a malabsorption disorder characterized by diarrhea andfailure to thrive.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:10~50 FC~~1:10~50

Images

Anti-PRSS7 Antibody (E979) at 1:1000 dilution + A549 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 113 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

PRSS7 Antibody (C-term E979) (Cat. APR03667G)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PRSS7 Antibody (C-term E979) for immunohistochemistry. Clinical relevance has not been evaluated.

PRSS7 Antibody (C-term E979) (Cat. APR03667G) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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