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PRDX4 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR03655G 100 μl / $495

PRDX4 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR03655G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PRDX4 Antibody (Center).

Molecular Weight

30540 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Secreted

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

82-110 aa

Target

This PRDX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-110 amino acids from the Central region of human PRDX4.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Probably involved in redox regulation of the cell. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.

Summary

The protein encoded by this gene is an antioxidant enzymeand belongs to the peroxiredoxin family. The protein is localizedto the cytoplasm. Peroxidases of the peroxiredoxin family reducehydrogen peroxide and alkyl hydroperoxides to water and alcoholwith the use of reducing equivalents derived from thiol-containingdonor molecules. This protein has been found to play a regulatoryrole in the activation of the transcription factor NF-kappaB.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:50~100

Images

PRDX4 Antibody (Center) (Cat. APR03655G) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the PRDX4 antibody detected the PRDX4 protein (arrow).

Western blot analysis of PRDX4 (arrow) using rabbit polyclonal PRDX4 Antibody (Center) (Cat. APR03655G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PRDX4 gene.

PRDX4 Antibody (Center) (Cat. APR03655G) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the PRDX4 antibody detected the PRDX4 protein (arrow).

Specification

Quantity

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