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FBXO21 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR03553G 100 μl / $495

FBXO21 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR03553G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FBXO21 Antibody (C-term).

Molecular Weight

72270 Da

Host

Rabbit

Species Reactivity

Mouse

Immunogen

474-501 aa

Target

This FBXO21 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 474-501 amino acids from the C-terminal region of human FBXO21.

Isotype

Rabbit Ig

Symbol

FBX21, KIAA0875

GeneID

UniProt ID

Function

Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex.

Summary

This gene encodes a member of the F-box protein familywhich is characterized by an approximately 40 amino acid motif, theF-box. The F-box proteins constitute one of the four subunits ofubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box),which function in phosphorylation-dependent ubiquitination. TheF-box proteins are divided into 3 classes: Fbws containing WD-40domains, Fbls containing leucine-rich repeats, and Fbxs containingeither different protein-protein interaction modules or norecognizable motifs. The protein encoded by this gene belongs tothe Fbxs class. Alternative splicing of this gene generates 2transcript variants.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:50~100

Images

FBXO21 Antibody (C-term) (Cat. APR03553G) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the FBXO21 antibody detected the FBXO21 protein (arrow).

FBXO21 Antibody (C-term) (Cat. APR03553G)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FBXO21 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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