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RNF19B Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR03535G 100 μl / $495

RNF19B Antibody (Center)

Brand

Leading Biology

Catalog Number

APR03535G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RNF19B Antibody (Center).

Molecular Weight

77925 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasmic granule membrane; Multi-pass membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

369-398 aa

Target

This RNF19B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 369-398 amino acids from the Central region of human RNF19B.

Isotype

Rabbit Ig

Symbol

IBRDC3, NKLAM

GeneID

UniProt ID

Function

E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as UCKL1. Involved in the cytolytic activity of natural killer cells and cytotoxic T-cells.

Summary

IBRDC3 is a cytolysis-associated transmembrane proteinexpressed in natural killer (NK) cells and T lymphocytes followingcytokine stimulation (Kozlowski et al., 1999 [PubMed10438909]).

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, FC, E

Dilution

WB~~1:500 FC~~1:10~50

Images

Anti-RNF19B Antibody (Center) at 1:500 dilution + THP-1 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 78 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

RNF19B Antibody (Center) (Cat. APR03535G) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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