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CD2BP2 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR03500G 100 μl / $495

CD2BP2 Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR03500G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD2BP2 Antibody (N-term).

Molecular Weight

37646 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Nucleus. Note=Predominantly nuclear

Host

Rabbit

Species Reactivity

Human

Immunogen

24-52 aa

Target

This CD2BP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-52 amino acids from the N-terminal region of human CD2BP2.

Isotype

Rabbit Ig

Symbol

KIAA1178

GeneID

UniProt ID

Function

Involved in pre-mRNA splicing as component of the U5 snRNP complex that is involved in spliceosome assembly.

Summary

This gene encodes a bi-functional protein. In thecytoplasm, the encoded protein binds the cytoplasmic tail of humansurface antigen CD2 via its C-terminal GYF domain, and regulateCD2-triggered T lymphocyte activation. In the nucleus, this proteinis a component of the U5 small nuclear ribonucleoprotein complexand is involved in RNA splicing. A pseudogene has been identifiedon chromosome 7. Alternative splicing results in multipletranscript variants but their biological validity has not beendetermined.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50

Images

CD2BP2 Antibody (N-term) (Cat. APR03500G) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CD2BP2 antibody detected the CD2BP2 protein (arrow).

CD2BP2 antibody(N-term) (Cat. APR03500G) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CD2BP2 antibody(N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

CD2BP2 Antibody (N-term) (Cat. APR03500G) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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