> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > MPP1 Antibody (Center)Brand |
Leading Biology | Catalog Number |
APR03467G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MPP1 Antibody (Center).
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Molecular Weight |
52296 Da
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Cellular Localization |
Antigen Cellular Localization:
Membrane; Lipid-anchor. Cell projection, stereocilium. Note=Colocalizes with WHRN at stereocilium tip during hair cell development (By similarity) Colocalizes with MPP5 in the retina, at the outer limiting membrane (OLM). Colocalizes with WHRN in the retina, at the outer limiting membrane (OLM), outer plexifirm layer (OPL), basal bodies and at the connecting cilium (CC). Colocalizes with NF2 in non- myelin-forming Schwann cells.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
301-327 aa
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Target |
This MPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 301-327 amino acids from the Central region of human MPP1.
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Isotype |
Rabbit Ig
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Symbol |
DXS552E, EMP55
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GeneID |
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UniProt ID |
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Function |
Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity (By similarity).
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Summary |
This gene encodes the prototype of the membrane-associatedguanylate kinase (MAGUK) family proteins. MAGUKs interact with thecytoskeleton and regulate cell proliferation, signaling pathways,and intercellular junctions. The encoded protein is an extensivelypalmitoylated membrane phosphoprotein containing a PDZ domain, aSrc homology 3 (SH3) motif, and a guanylate kinase domain. Thisgene product interacts with various cytoskeletal proteins and celljunctional proteins in different tissue and cell types, and may beinvolved in the regulation of cell shape, hair cell development,neural patterning of the retina, and apico-basal polarity and tumorsuppression pathways in non-erythroid cells. Multiple transcriptvariants encoding different isoforms have been found for this gene.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, FC, E
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Dilution |
WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
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Images |
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Specification |
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Quantity |
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| 5 | Leading Biology | APR04349G | HECTD2 Antibody (N-term) | 100 μl | Polyclonal Antibodies |
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| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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