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CLDN22 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR03429G 100 μl / $495

CLDN22 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR03429G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CLDN22 Antibody (Center).

Molecular Weight

24509 Da

Cellular Localization

Antigen Cellular Localization: Cell junction, tight junction. Cell membrane; Multi-pass membrane protein

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

90-117 aa

Target

This CLDN22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-117 amino acids from the Central region of human CLDN22.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity.

Summary

This gene encodes a member of the claudin family. Claudinsare integral membrane proteins and components of tight junctionstrands. Tight junction strands serve as a physical barrier toprevent solutes and water from passing freely through theparacellular space between epithelial or endothelial cell sheets,and also play critical roles in maintaining cell polarity andsignal transductions. This gene is intronless and overlaps the 3'UTR of the WWC2 gene (GeneID: 80014) on the opposite strand.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, FC, E

Dilution

WB~~1:1000 FC~~1:10~50

Images

CLDN22 Antibody (Center) (Cat. APR03429G) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the CLDN22 antibody detected the CLDN22 protein (arrow).

CLDN22 Antibody (Center) (Cat. APR03429G) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the CLDN22 antibody detected the CLDN22 protein (arrow).

CLDN22 Antibody (Center) (Cat. APR03429G) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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