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TIMP4 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR03420G 100 μl / $495

TIMP4 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR03420G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TIMP4 Antibody (Center).

Molecular Weight

25503 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

48-74 aa

Target

This TIMP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-74 amino acids from the Central region of human TIMP4.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP- 9.

Summary

This gene belongs to the TIMP gene family. The proteinsencoded by this gene family are inhibitors of the matrixmetalloproteinases, a group of peptidases involved in degradationof the extracellular matrix. The secreted, netrin domain-containingprotein encoded by this gene is involved in regulation of plateletaggregation and recruitment and may play role in hormonalregulation and endometrial tissue remodeling.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:50~100

Images

TIMP4 Antibody (Center) (Cat. APR03420G) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the TIMP4 antibody detected the TIMP4 protein (arrow).

TIMP4 Antibody (Center) (Cat. APR03420G) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the TIMP4 antibody detected the TIMP4 protein (arrow).

TIMP4 Antibody (Center) (Cat. APR03420G) immunohistochemistry analysis in formalin fixed and paraffin embedded mouse heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TIMP4 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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