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ADAMTS10 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR03418G 100 μl / $495

ADAMTS10 Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR03418G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ADAMTS10 Antibody (N-term).

Molecular Weight

120874 Da

Cellular Localization

Antigen Cellular Localization: Secreted, extracellular space, extracellular matrix

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

210-240 aa

Target

This ADAMTS10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-240 amino acids from the N-terminal region of human ADAMTS10.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Metalloprotease that participate in microfibrils assembly. Microfibrils are extracellular matrix components occurring independently or along with elastin in the formation of elastic tissues.

Summary

This gene belongs to the ADAMTS (a disintegrin andmetalloproteinase domain with thrombospondin type-1 motifs) familyof zinc-dependent proteases. ADAMTS proteases are complex secretedenzymes containing a prometalloprotease domain of the reprolysintype attached to an ancillary domain with a highly conservedstructure that includes at least one thrombospondin type 1 repeat.They have been demonstrated to have important roles in connectivetissue organization, coagulation, inflammation, arthritis,angiogenesis and cell migration. The product of this gene plays amajor role in growth and in skin, lens, and heart development. Itis also a candidate gene for autosomal recessive Weill-Marchesanisyndrome.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

ADAMTS10 Antibody (N-term) (Cat. APR03418G) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the ADAMTS10 antibody detected the ADAMTS10 protein (arrow).

Specification

Quantity

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