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ICOS Antibody (internal region)

Catalog # Availability Size / Price Inquiry
APG00605G 0.1mg / $495

ICOS Antibody (internal region)

Brand

Leading Biology

Catalog Number

APG00605G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ICOS Antibody (internal region).

Molecular Weight

22625 Da

Cellular Localization

Antigen Cellular Localization: Isoform 1: Cell membrane; Single-pass type I membrane protein

Host

Goat

Isotype

IgG

Symbol

AILIM

GeneID

UniProt ID

Function

Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up- regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up- regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre- activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes (By similarity).

Form

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

E

Images

Specification

Quantity

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