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Recombinant Human WISP1 Protein(C-His Tag)Brand |
Leading Biology | Catalog Number |
PH0154M1 |
Product Type |
Cytokine | Field of Research |
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Nature |
Recombinant Protein
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Expression Host |
Mammalian cell
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Species |
Human
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AA Sequence |
NP_003873.1(Met 1-Asn 367)
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Tags |
C-His
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Molecular Weight |
55KD
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Form |
lyophilized |
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Purity |
Greater than 95% by SDS-PAGE |
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Storage & Stability |
-70°C
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Storage Buffer |
0.2 μm filtered PBS, pH7.4
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Product Description |
WNT1-inducible-signaling pathway protein 1 (WISP-1), also known as CCN4, is a matricellular protein that in humans is encoded by the WISP1 gene. WISP-1 is highly homologous to CYR61 (CCN1) and CTGF (CCN2), and is a member of the CCN family of secreted, extracellular matrix (ECM)-associated signaling proteins (CCN intercellular signaling protein). The CCN family of proteins shares a common molecular protein structure, characterized by an N-terminal secretory signal peptide followed by four distinct domains with homologies to insulin-like growth factor binding protein (IGFBP), von Willebrand type C repeats (vWC), thrombospondin type 1 repeat (TSR), and a cysteine knot motif within the C-terminal (CT) domain. This family of proteins regulates diverse cellular functions, including cell adhesion, migration, proliferation, differentiation, and survival.
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Synonyms |
CCN4 Protein(Human); WISP1c Protein(Human); WISP1i Protein(Human); WISP1tc Protein(Human)
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Images |
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Quantity |
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$325.00 | Add Ask |
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