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Recombinant Human TNFRSF10B Protein(C-His Tag)

PH0145M1

Catalog #	Availability	Size / Price	Inquiry
PH0145M1-20μg		20μg / $325
PH0145M1-100μg		100μg / $955

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Leading Biology Inc.

tel:1-661-524(LBI)-0262
Info@leadingbiology.com

Brand	Leading Biology	Catalog Number	PH0145M1
Product Type	Cytokine	Field of Research
Nature	Recombinant Protein
Expression Host	Mammalian cell
Species	Human
AA Sequence	NP_003833.3(Met 1-Glu 182)
Tags	C-His
Molecular Weight	20KD
Form	lyophilized
Purity	Greater than 95% by SDS-PAGE
Storage & Stability	-70°C
Storage Buffer	0.2 μm filtered PBS, pH7.4
Product Description	Receptor for the cytotoxic ligand TNFSF10/TRAIL . The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.
Synonyms	DR5 / TRAIL R2 Protein(Human); CD262 Protein(Human); DR5 Protein(Human); KILLER Protein(Human); KILLER/DR5 Protein(Human); TRAIL-R2 Protein(Human); TRAILR2 Protein(Human); TRICK2 Protein(Human); TRICK2A Protein(Human); TRICK2B Protein(Human); TRICKB Protein(Human); ZTNFR9 Protein(Human)
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