> Proteins, Peptides & Amino Acids > Recombinant Protein > Cytokine > Recombinant Mouse THPO Protein(N-His Tag)Brand |
Leading Biology | Catalog Number |
PM0144M3 |
Product Type |
Cytokine | Field of Research |
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Nature |
Recombinant Protein
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Expression Host |
Mammalian cell
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Species |
Mouse
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AA Sequence |
NP_033405.1(Met 1-Thr 356)
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Tags |
N-His
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Molecular Weight |
85KD
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Form |
lyophilized |
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Purity |
Greater than 95% by SDS-PAGE |
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Storage & Stability |
-70°C
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Storage Buffer |
0.2 μm filtered PBS, pH7.4
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Product Description |
Thrombopoietin (THPO) also known as megakaryocyte growth and development factor (MGDF) is a protein that in humans is encoded by the THPO gene. Thrombopoietin is a glycoprotein hormone produced by the liver and kidney which regulates the production of platelets. It stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets. Megakaryocytopoiesis is the cellular development process that leads to platelet production. The protein encoded by this gene is a humoral growth factor necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene.
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Synonyms |
MGDF Protein(Mouse); MKCSF Protein(Mouse); ML Protein(Mouse); MPLLG Protein(Mouse); THCYT1 Protein(Mouse); TPO Protein(Mouse)
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Images |
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Quantity |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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