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Location: Home > Proteins, Peptides & Amino Acids > Recombinant Protein > Cytokine > Recombinant Human BCMA Protein(C-His Tag)

Recombinant Human BCMA Protein(C-His Tag)

PH0097M1
Catalog # Availability Size / Price Inquiry
PH0097M1-20μg 20μg / $325
PH0097M1-100μg 100μg / $955

Recombinant Human BCMA Protein(C-His Tag)

Brand

Leading Biology

Catalog Number

PH0097M1

Product Type

Cytokine

Field of Research

Nature

Recombinant Protein

Expression Host

Mammalian cell

Species

Human

AA Sequence

NP_001183.2(Met1-Ala54)

Tags

C-His

Molecular Weight

8KD

Activity

Measured by its ability to inhibit APRIL-mediated proliferation of anti-IgM stimulated mouse B cells.

Form

lyophilized

Purity

Greater than 95% by SDS-PAGE

Storage & Stability

-70°C

Storage Buffer

0.2 μm filtered PBS, pH7.4

Product Description

B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene. TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.

Synonyms

BCM Protein(Human); CD269 Protein(Human); TNFRSF13A Protein(Human)

Images

Quantity

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