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Location: Home > Custom Services > Sequencing and Chip Technology > Whole Exome Sequencing

Whole Exome Sequencing

Date: 2018-01-25 Author: Leading Biology Click: 996

Introduction

The whole-exome sequencing (WES) is a genomic technique for sequencing all of the protein-coding genes in a genome (known as the exome). It consists of two steps: the first step is to select only the subset of DNA that encodes proteins. And the second step is to sequence the exonic DNA using any high-throughput DNA sequencing technology. Exome sequencing can efficiently identify coding variants across a wide range of applications, including population genetics, genetic disease, and cancer studies.


Whole Exome Sequencing


The WES advantages are: 

(1). Identifies variants across a wide range of applications. 

(2). Achieves comprehensive coverage of coding regions. 

(3). Provides a cost-effective alternative to whole-genome sequencing. 

(4). Produces a smaller, more manageable data set for faster, easier analysis compared to whole-genome approaches.

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