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Phospho-PPP1CA-T320 pAb

Catalog # Availability Size / Price Inquiry
AMR01069N-1 50ul / $395
AMR01069N-2 100ul / $495
AMR01069N-3 200ul / $595

Phospho-PPP1CA-T320 pAb

Brand

Leading Biology

Catalog Number

AMR01069N

Product Type

Phosphorylated Antibodies

Field of Research

Epigenetics & Nuclear Signaling>Epigenetic writers and erasers of core Histones

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-PPP1CA-T320 pAb.

Molecular Weight

Calculated MW: 32kDa/37kDa/38kDa Observed MW: 38kDa

Species Reactivity

Rabbit

Immunogen

A phospho specific peptide corresponding to residues surrounding T320 of human PPP1CA

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100

Product Description

The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Synonyms

PPP1CA; PP-1A; PP1A; PP1alpha; PPP1A; protein phosphatase 1 catalytic subunit alpha

Images

Western blot analysis of extracts of various cell lines, using Phospho-PPP1CA-T320 antibody.

Immunohistochemistry of paraffin-embedded rat lung using Phospho-PPP1CA-T320 antibody.

Immunohistochemistry of paraffin-embedded human lung cancer using Phospho-PPP1CA-T320 antibody.

Specification

Quantity

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