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Phospho-PLCG2-Y759 pAb

Catalog # Availability Size / Price Inquiry
AMR01068N-1 50ul / $395
AMR01068N-2 100ul / $495
AMR01068N-3 200ul / $595

Phospho-PLCG2-Y759 pAb

Brand

Leading Biology

Catalog Number

AMR01068N

Product Type

Phosphorylated Antibodies

Field of Research

Cardiovascular>Angiogenesis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-PLCG2-Y759 pAb.

Molecular Weight

Calculated MW: 147kDa Observed MW: 150kDa

Species Reactivity

Rabbit

Immunogen

A synthetic phosphorylated peptide around Y759 of human PLCG2 (NP_002652.2).

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.

Synonyms

PLCG2; APLAID; FCAS3; PLC-IV; PLC-gamma-2; phospholipase C gamma 2

Images

Western blot analysis of extracts of Raji cells, using Phospho-PLCG2-Y759 antibody.

Specification

Quantity

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