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Phospho-GRIN2B-Y1474 pAb

Catalog # Availability Size / Price Inquiry
AMR00905N-1 50ul / $395
AMR00905N-2 100ul / $495
AMR00905N-3 200ul / $595

Phospho-GRIN2B-Y1474 pAb

Brand

Leading Biology

Catalog Number

AMR00905N

Product Type

Phosphorylated Antibodies

Field of Research

Neuroscience>Neurodegenerative Diseases

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-GRIN2B-Y1474 pAb.

Molecular Weight

Calculated MW: 166kDa Observed MW: 200kDa

Species Reactivity

Rabbit

Immunogen

A phospho specific peptide corresponding to residues surrounding Y1474 of human GRIN2B

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.

Synonyms

GRIN2B; EIEE27; GluN2B; MRD6; NMDAR2B; NR2B; hNR3; glutamate receptor ionotropic, NMDA 2B

Images

Western blot analysis of extracts from A431 cells, using Phospho-GRIN2B-Y1474 antibody.

Specification

Quantity

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