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Phospho-GRIN2B-Y1474 pAbBrand |
Leading Biology | Catalog Number |
AMR00905N |
Product Type |
Phosphorylated Antibodies | Field of Research |
Neuroscience>Neurodegenerative Diseases |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Phospho-GRIN2B-Y1474 pAb.
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Molecular Weight |
Calculated MW:
166kDa
Observed MW:
200kDa
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Species Reactivity |
Rabbit
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Immunogen |
A phospho specific peptide corresponding to residues surrounding Y1474 of human GRIN2B
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Cross Reactivity |
Human
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB
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Dilution |
WB 1:500 - 1:2000
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Product Description |
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.
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Synonyms |
GRIN2B; EIEE27; GluN2B; MRD6; NMDAR2B; NR2B; hNR3; glutamate receptor ionotropic, NMDA 2B
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Images |
Western blot analysis of extracts from A431 cells, using Phospho-GRIN2B-Y1474 antibody. |
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Specification |
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Quantity |
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