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Location: Home > Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > TNFRSF8/CD30 Antibody (Center) (Ascites)

TNFRSF8/CD30 Antibody (Center) (Ascites)

Catalog # Availability Size / Price Inquiry
AMM02429G 0.1 ml / $495

TNFRSF8/CD30 Antibody (Center) (Ascites)

Brand

Leading Biology

Catalog Number

AMM02429G

Product Type

Monoclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TNFRSF8/CD30 Antibody (Center) (Ascites).

Molecular Weight

63747 Da

Cellular Localization

Antigen Cellular Localization: Isoform 1: Cell membrane; Single-pass type I membrane protein

Host

Mouse

Species Reactivity

Human

Immunogen

294-321 aa

Target

This TNFRSF8/CD30 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 294-321 amino acids from the Central region of human TNFRSF8/CD30.

Clone

595CT15.5.1

Isotype

IgG1

Symbol

CD30, D1S166E

GeneID

UniProt ID

Function

Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF- kappa-B.

Summary

The protein encoded by this gene is a member of theTNF-receptor superfamily. This receptor is expressed by activated,but not by resting, T and B cells. TRAF2 and TRAF5 can interactwith this receptor, and mediate the signal transduction that leadsto the activation of NF-kappaB. This receptor is a positiveregulator of apoptosis, and also has been shown to limit theproliferative potential of autoreactive CD8 effector T cells andprotect the body against autoimmunity. Two alternatively splicedtranscript variants of this gene encoding distinct isoforms havebeen reported.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:100~1000

Images

TNFRSF8/CD30 Antibody (Center)(Ascites)(Cat. AMM02429G) western blot analysis in K562 cell line lysates (35μg/lane).This demonstrates the TNFRSF8/CD30 antibody detected the TNFRSF8/CD30 protein (arrow).

Specification

Quantity

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