> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > EPCAM Antibody (Ascites)Brand |
Leading Biology | Catalog Number |
AMM02428G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality EPCAM Antibody (Ascites).
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Molecular Weight |
34932 Da
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Cellular Localization |
Antigen Cellular Localization:
Lateral cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Note=Colocalizes with CLDN7 at the lateral cell membrane and tight junction
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Host |
Mouse
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Species Reactivity |
Human
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Immunogen |
59-86 aa
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Target |
This EPCAM antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 59-86 amino acids from human EPCAM.
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Clone |
463CT25.1.1
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Isotype |
IgG1
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Symbol |
GA733-2, M1S2, M4S1, MIC18, TACSTD1, TRO
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GeneID |
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UniProt ID |
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Function |
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
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Summary |
This gene encodes a carcinoma-associated antigen and is amember of a family that includes at least two type I membraneproteins. This antigen is expressed on most normal epithelial cellsand gastrointestinal carcinomas and functions as a homotypiccalcium-independent cell adhesion molecule. The antigen is beingused as a target for immunotherapy treatment of human carcinomas.Mutations in this gene result in congenital tufting enteropathy.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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