> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Monoclonal Antibodies > CST3 AntibodyBrand |
Leading Biology | Catalog Number |
AMM02427G |
Product Type |
Monoclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CST3 Antibody.
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Molecular Weight |
15799 Da
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Cellular Localization |
Antigen Cellular Localization:
Secreted.
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Host |
Mouse
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Species Reactivity |
Human
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Immunogen |
95-122 aa
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Target |
This CST3 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 95-122 amino acids from human CST3.
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Clone |
572CT4.3.2
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Isotype |
IgG1
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GeneID |
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UniProt ID |
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Function |
As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity.
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Summary |
The cystatin superfamily encompasses proteins that containmultiple cystatin-like sequences. Some of the members are activecysteine protease inhibitors, while others have lost or perhapsnever acquired this inhibitory activity. There are three inhibitoryfamilies in the superfamily, including the type 1 cystatins(stefins), type 2 cystatins and the kininogens. The type 2 cystatinproteins are a class of cysteine proteinase inhibitors found in avariety of human fluids and secretions, where they appear toprovide protective functions. The cystatin locus on chromosome 20contains the majority of the type 2 cystatin genes and pseudogenes.This gene is located in the cystatin locus and encodes the mostabundant extracellular inhibitor of cysteine proteases, which isfound in high concentrations in biological fluids and is expressedin virtually all organs of the body. A mutation in this gene hasbeen associated with amyloid angiopathy. Expression of this proteinin vascular wall smooth muscle cells is severely reduced in bothatherosclerotic and aneurysmal aortic lesions, establishing itsrole in vascular disease.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:100~800
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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