> Proteins, Peptides & Amino Acids > Recombinant Protein > Cytokine > Recombinant Mouse NGF ProteinBrand |
Leading Biology | Catalog Number |
PM0133M2 |
Product Type |
Cytokine | Field of Research |
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Nature |
Recombinant Protein
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Expression Host |
Mammalian cell
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Species |
Mouse
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AA Sequence |
NP_001106168.1(Ser 122-Gly 241)
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Tags |
Tag-Free
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Molecular Weight |
14KD
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Form |
lyophilized |
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Purity |
Greater than 95% by SDS-PAGE |
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Storage & Stability |
-70°C
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Storage Buffer |
0.2 μm filtered 20mM NaAc, 150mM NaCl, pH 5.5
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Product Description |
Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide primarily involved in the regulation of growth, maintenance, proliferation, and survival of certain target neurons. It is perhaps the prototypical growth factor, in that it was one of the first to be described. Since it was first isolated by Nobel Laureates Rita Levi-Montalcini and Stanley Cohen in 1956, numerous biological processes involving NGF have been identified, two of them being the survival of pancreatic beta cells and the regulation of the immune system. As its name suggests, NGF is involved primarily in the growth, as well as the maintenance, proliferation, and survival of nerve cells (neurons). In fact, NGF is critical for the survival and maintenance of sympathetic and sensory neurons, as they undergo apoptosis in its absence. However, several recent studies suggest that NGF is also involved in pathways besides those regulating the life cycle of neurons.
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Synonyms |
Beta-NGF Protein(Mouse); HSAN5 Protein(Mouse); NGFB Protein(Mouse)
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Images |
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Quantity |
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Tel: 1-661-524(LBI)-0262
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