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Recombinant Mouse FGFR1 Protein(C-His Tag)Brand |
Leading Biology | Catalog Number |
PM0112M1 |
Product Type |
Cytokine | Field of Research |
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Nature |
Recombinant Protein
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Expression Host |
Mammalian cell
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Species |
Mouse
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AA Sequence |
P16092-1(Met 1-Glu 376)
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Tags |
C-His
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Molecular Weight |
55KD
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Form |
lyophilized |
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Purity |
Greater than 95% by SDS-PAGE |
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Storage & Stability |
-70°C
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Storage Buffer |
0.2 μm filtered PBS, pH7.4
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Product Description |
Fibroblast growth factor receptor 1 (FGFR1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome, and CD331, is a receptor tyrosine kinase whose ligands are specific members of the fibroblast growth factor family. FGFR1 has been shown to be associated with Pfeiffer syndrome. Mice genetically engineered to lack a functional Fgfr1 gene (ortholog of the human FGFR1 gene) die in utero before 10.5 days of gestation. Embryos exhibit extensive deficiencies in the development and organization of mesoderm-derived tissues and the musculoskeletal system. The Fgfr1 gene appears critical for the truncation of embryonic structures and formation of muscle and bone tissues and thereby the normal formation of limbs, skull, outer, middle, and inner ear, neural tube, tail, and lower spine as well as normal hearing.
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Synonyms |
bFGF-R-1 Protein(Mouse); BFGFR Protein(Mouse); CD331 Protein(Mouse); CEK Protein(Mouse); FGFBR Protein(Mouse); FLG Protein(Mouse); FLT-2 Protein(Mouse); FLT2 Protein(Mouse); HBGFR Protein(Mouse); HH2 Protein(Mouse); HRTFDS Protein(Mouse); KAL2 Protein(Mouse); N-SAM Protein(Mouse); OGD Protein(Mouse)
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Images |
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Quantity |
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|
$325.00 | Add Ask |
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