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Location: Home > Proteins, Peptides & Amino Acids > Recombinant Protein > Cytokine > Recombinant Mouse FGFR1 Protein(C-His Tag)

Recombinant Mouse FGFR1 Protein(C-His Tag)

PM0112M1
Catalog # Availability Size / Price Inquiry
PM0112M1-20μg 20μg / $325
PM0112M1-100μg 100μg / $955

Recombinant Mouse FGFR1 Protein(C-His Tag)

Brand

Leading Biology

Catalog Number

PM0112M1

Product Type

Cytokine

Field of Research

Nature

Recombinant Protein

Expression Host

Mammalian cell

Species

Mouse

AA Sequence

P16092-1(Met 1-Glu 376)

Tags

C-His

Molecular Weight

55KD

Form

lyophilized

Purity

Greater than 95% by SDS-PAGE

Storage & Stability

-70°C

Storage Buffer

0.2 μm filtered PBS, pH7.4

Product Description

Fibroblast growth factor receptor 1 (FGFR1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome, and CD331, is a receptor tyrosine kinase whose ligands are specific members of the fibroblast growth factor family. FGFR1 has been shown to be associated with Pfeiffer syndrome. Mice genetically engineered to lack a functional Fgfr1 gene (ortholog of the human FGFR1 gene) die in utero before 10.5 days of gestation. Embryos exhibit extensive deficiencies in the development and organization of mesoderm-derived tissues and the musculoskeletal system. The Fgfr1 gene appears critical for the truncation of embryonic structures and formation of muscle and bone tissues and thereby the normal formation of limbs, skull, outer, middle, and inner ear, neural tube, tail, and lower spine as well as normal hearing.

Synonyms

bFGF-R-1 Protein(Mouse); BFGFR Protein(Mouse); CD331 Protein(Mouse); CEK Protein(Mouse); FGFBR Protein(Mouse); FLG Protein(Mouse); FLT-2 Protein(Mouse); FLT2 Protein(Mouse); HBGFR Protein(Mouse); HH2 Protein(Mouse); HRTFDS Protein(Mouse); KAL2 Protein(Mouse); N-SAM Protein(Mouse); OGD Protein(Mouse)

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Quantity

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