> Proteins, Peptides & Amino Acids > Recombinant Protein > Cytokine > Recombinant Human CXCL12 ProteinBrand |
Leading Biology | Catalog Number |
PH0081E2 |
Product Type |
Cytokine | Field of Research |
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Nature |
Recombinant Protein
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Expression Host |
E.coli
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Species |
Human
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AA Sequence |
P48061-1(Lys 22-Met 93)
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Tags |
Tag-Free
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Molecular Weight |
12KD
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Activity |
Measured by its ability to chemoattract 5-10 day cultured human peripheral blood lymphocytes (PBL).
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Form |
lyophilized |
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Purity |
Greater than 95% by SDS-PAGE |
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Storage & Stability |
-70°C
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Storage Buffer |
0.2 μm filtered PBS, pH7.4
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Product Description |
The C-X-C motif chemokine 12 (CXCL12), also known as stromal cell-derived factor 1 (SDF1), is a chemokine protein that in humans is encoded by the CXCL12 gene on chromosome 10. It is ubiquitously expressed in many tissues and cell types. Stromal cell-derived factors 1-alpha and 1-beta are small cytokines that belong to the chemokine family, members of which activate leukocytes and are often induced by proinflammatory stimuli such as lipopolysaccharide, TNF, or IL1. The chemokines are characterized by the presence of 4 conserved cysteines that form 2 disulfide bonds. They can be classified into 2 subfamilies. In the CC subfamily, the cysteine residues are adjacent to each other. In the CXC subfamily, they are separated by an intervening amino acid. The SDF1 proteins belong to the latter group. CXCL12 signaling has been observed in several cancers. The CXCL12 gene also contains one of 27 SNPs associated with increased risk of coronary artery disease.
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Synonyms |
IRH Protein(Human); PBSF Protein(Human); SCYB12 Protein(Human); SDF-1 Protein(Human); SDF1 Protein(Human); TLSF Protein(Human); TPAR1 Protein(Human)
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Images |
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Quantity |
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| Select | Brand | Catalog No. | Product Name | Pack Size | Type | Field of Research | Specification | Quantity | Price(USD) | |
| 1 | Leading Biology | PH0003E1 | Recombinant Human TNF Alpha Protein | 10ug | Cytokine |
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$195.00 | Add Ask | ||
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| 3 | Leading Biology | PH0073E2 | Recombinant Human CXCL2 Protein | 20μg | Cytokine |
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$325.00 | Add Ask | ||
| 4 | Leading Biology | PH0041M1 | Recombinant Human IL-34 Protein (C-His Tag) | 20μg | Cytokine |
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$325.00 | Add Ask | ||
| 5 | Leading Biology | PH0024E3 | Recombinant Human IL-16 Protein (N-His Tag) | 20μg | Cytokine |
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$325.00 | Add Ask | ||
| 6 | Leading Biology | PM0036M1 | Recombinant Mouse IL-28A Protein (C-His Tag) | 20μg | Cytokine |
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$325.00 | Add Ask |
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Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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