The ubiquitin proteasome system

The ubiquitin-proteasome system mediates 80%-85% protein degradation in eukaryotes. In addition to being involved in protein degradation, ubiquitination is also involved in almost all life activities, including cell cycle regulation, proliferation, apoptosis, differentiation, transcriptional regulation, gene expression, transcriptional regulation, signal transmission, injury repair, and inflammation immunity. Ubiquitination is associated with the pathogenesis of diseases such as cancer and cardiovascular diseases. Therefore, it has become a new target for new drug development.

Our Advantages

• High-throughput: identify and quantify up to thousands of proteins at once

• High precision and accuracy: accurate identification of modified peptides and modification sites

• 100% coverage: Use 2-3 enzymes for protein digestion to ensure full-coverage

• Ability to analyze low abundance ubiquitin-proteins

Overview of Protein Ubiquitination Analysis

Leading Biology is able to help you address research problems of ubiquitination identification and quantification. Through comprehensive protein ubiquitination analysis services, including protein extraction, digestion, peptide enrichment, LC-MS/MS analysis, data analysis and bioinformatics analysis, we can quickly, accurately and efficiently analyze the changes of various disease-related protein modifications to meet the needs of biomarker identification and drug target screening.

The workflow of protein ubiquitination analysis

Why Leading Biology?

At Leading Biology, we custom protein purification design for every single protein to ensure the production and recovery rate as high as possible.

Working with us, you will get stability, and it means a reliable partner to help streamline your R&D process.

Working with us, you will get the guaranteed service to accommodate your requirements.

· Innovative configurations of chromatography columns custom-tailored to each protein

· Vigorous quality control system to ensure the required quality and reproducibility

· Production capacity of up to tens of grams

· Flexible scale-up protein production

· Competitive price with fast turnaround time

Contact Information

Please obtain a quote before ordering, and refer to the quote number when you place an order.

Orders are typically confirmed within 12 hours.

Have a Question? Email us info@leadingbiology.com

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By Phone: 1-661-524(LBI)-0262 (USA)