Introduction

Many systems are either dynamically or stationary inhomogeneous and the inhomogeneities, especially dynamic inhomogeneities, are the key to understand their interactions and functions. 

Ensemble measurements naturally can only yield the mean value of the ensemble. Single-molecule trajectories on the other hand are direct records of the fluctuation that contain detailed dynamical and statistical information. Since trajectories may vary for different members of the ensemble the average trajectory contains less information, the ensemble might not even show fluctuations at all as they could be averaged out during the time span of the experiment.

Single Molecule Protein Detection

Single molecule array testing is a powerful new technique that is orders of magnitude more sensitive than standard sandwich based immunoassay techniques. Traditional ELISA measurements are limited to pg/ml levels of detection. 

How It Works

Simoa is based upon the isolation of individual immunocomplexes on paramagnetic beads using standard ELISA reagents. The main difference between Simoa and conventional immunoassays lies in the ability to trap single molecules in femtoliter-sized wells, allowing for a “digital” readout of each individual bead to determine if it is bound to the target analyte or not.

Why Leading Biology?

At Leading Biology, we custom protein purification design for every single protein to ensure the production and recovery rate as high as possible.

Working with us, you will get stability, and it means a reliable partner to help streamline your R&D process.

Working with us, you will get the guaranteed service to accommodate your requirements.

· Innovative configurations of chromatography columns custom-tailored to each protein

· Vigorous quality control system to ensure the required quality and reproducibility

· Production capacity of up to tens of grams

· Flexible scale-up protein production

· Competitive price with fast turnaround time

Contact Information

Please obtain a quote before ordering, and refer to the quote number when you place an order.

Orders are typically confirmed within 12 hours.

Have a Question? Email us info@leadingbiology.com

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By Phone: 1-661-524(LBI)-0262 (USA)