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ELABELA (human) Elisa

Catalog # Availability Size / Price Inquiry
EH0003 96T / $965

ELABELA (human) Elisa

Brand

Leading Biology

Catalog Number

EH0003

Product Type

ELISA Kit

Field of Research

Host

Rabbit IgG

Immunogen

Synthetic peptide H-Gln-Arg-Pro-Val-Asn-Leu-Thr-Met-Arg-Arg-Lys-LeuArg-Lys-His-Asn-Cys-Leu-Gln-Arg-Arg-Cys-Met-Pro-Leu-His-Ser-ArgVal-Pro-Phe-Pro-OH, (disulfide bridge), coupled to carrier protein

Form

Formulated for extracted samples (EIAH type)

Storage & Stability

One year from production date. Store refrigerated at 4° - 8°C.

Applications

This ELISA has been validated with the included reagents. It is intended to be used with appropriately extracted samples (original protocol III, Std.Ab1hr.Bt). For research use only

Product Description

ELABELA is a 32-amino acid peptide hormone that binds to the Apelin receptor. It bears 2 conserved di-arginine motifs (R31/R32 and R42/R43) suggesting that it may be further processed by Furin-like endopeptidases. Its function is crucial for heart development during embryogenesis and it needs to be secreted to become active since deletion of 7 residues in its signal peptide causes a complete loss-of-function in zebrafish.

This ELISA was developed with serum from rabbits immunized with ELABELA coupled to a carrier protein.

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