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ELABELA (rat) Elisa

Catalog # Availability Size / Price Inquiry
ER0001 96 tests / $545

ELABELA (rat) Elisa

Brand

Leading Biology

Catalog Number

ER0001

Product Type

ELISA Kit

Field of Research

Host

Rabbit IgG

Immunogen

Synthetic peptide NH2-Glu-Lys-Ser-Val-Asn-Phe-Pro-Arg-Arg-Arg-LysLeu-Tyr-Arg-His-Asn-Cys-Phe-Arg-Arg-Arg-Cys-Ile-Ser-Leu-His-SerArg-Val-Pro-Phe-Pro-OH (Disulfide bond Cys17 & Cys22), coupled to carrier protein.

Form

Formulated for extracted samples (EIAH type).

Purity

Range: 0-100ng/ml Average IC50: 2ng/ml

Storage & Stability

One year from production date. Store refrigerated at 4° - 8°C

Applications

This ELISA has been validated with the included reagents. It is intended to be used with appropriately extracted samples (original protocol III, Std.Ab1hr.Bt).

Product Description

ELABELA is a 32-amino acid peptide hormone that binds to the Apelin receptor. It bears 2 conserved di-arginine motifs (R31/R32 and R42/R43) suggesting that it may be further processed by Furin-like endopeptidases. Its function is crucial for heart development during embryogenesis and it needs to be secreted to become active since deletion of 7 residues in its signal peptide causes a complete loss-of-function in zebrafish.


This ELISA was developed with serum from rabbits immunized with ELABELA coupled to a carrier protein.

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