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Phospho-CDK9-T186 pAb

Catalog # Availability Size / Price Inquiry
AMR01092N-1 50ul / $395
AMR01092N-2 100ul / $495
AMR01092N-3 200ul / $595

Phospho-CDK9-T186 pAb

Brand

Leading Biology

Catalog Number

AMR01092N

Product Type

Phosphorylated Antibodies

Field of Research

Cell Biology & Developmental Biology>Cell Cycle

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-CDK9-T186 pAb.

Molecular Weight

Calculated MW: 42kDa/53kDa Observed MW: Refer to figures

Species Reactivity

Rabbit

Immunogen

A synthetic phosphorylated peptide around T186 of human CDK9 (NP_001252.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.

Synonyms

CDK9; C-2k; CDC2L4; CTK1; PITALRE; TAK; cyclin-dependent kinase 9

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