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Phospho-CBX3-S83 pAb

Catalog # Availability Size / Price Inquiry
AMR01084N-1 50ul / $395
AMR01084N-2 100ul / $495
AMR01084N-3 200ul / $595

Phospho-CBX3-S83 pAb

Brand

Leading Biology

Catalog Number

AMR01084N

Product Type

Phosphorylated Antibodies

Field of Research

Protein phosphorylation

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-CBX3-S83 pAb.

Molecular Weight

Calculated MW: 20kDa Observed MW: 21kDa

Species Reactivity

Rabbit

Immunogen

A phospho specific peptide corresponding to residues surrounding S83 of human CBX3

Cross Reactivity

Human

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.

Synonyms

CBX3; HECH; HP1-GAMMA; HP1Hs-gamma; chromobox 3

Images

Western blot analysis of extracts of A431 cells, using Phospho-CBX3-S83 antibody.

Specification

Quantity

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