> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Phosphorylated Antibodies > Phospho-ACLY-S455 pAbBrand |
Leading Biology | Catalog Number |
AMR01062N |
Product Type |
Phosphorylated Antibodies | Field of Research |
Endocrine & Metabolism>Insulin Receptor Signaling Pathway |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Phospho-ACLY-S455 pAb.
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Molecular Weight |
Calculated MW:
91kDa/119kDa/120kDa
Observed MW:
121kDa
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Species Reactivity |
Rabbit
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Immunogen |
A synthetic phosphorylated peptide around S455 of human ACLY (NP_001087.2).
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Cross Reactivity |
Mouse,Rat
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB,IHC,IP
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Dilution |
WB 1:500 - 1:2000
IHC 1:50 - 1:100
IP 1:50 - 1:100
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Product Description |
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
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Synonyms |
ACLY; ACL; ATPCL; CLATP; ATP citrate lyase
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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