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Phospho-VASP-S157 pAb

Catalog # Availability Size / Price Inquiry
AMR01047N-1 50ul / $395
AMR01047N-2 100ul / $495
AMR01047N-3 200ul / $595

Phospho-VASP-S157 pAb

Brand

Leading Biology

Catalog Number

AMR01047N

Product Type

Phosphorylated Antibodies

Field of Research

Cell Biology & Developmental Biology>Cytoskeleton

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-VASP-S157 pAb.

Molecular Weight

Calculated MW: 39kDa Observed MW: 50kDa

Species Reactivity

Rabbit

Immunogen

A synthetic phosphorylated peptide around S157 of human VASP (NP_003361.1).

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IP

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100 IP 1:50 - 1:100

Product Description

Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.

Synonyms

VASP; vasodilator-stimulated phosphoprotein

Images

Western blot analysis of extracts of A431 cells, using Phospho-VASP-S157 antibody.

Specification

Quantity

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