> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Phosphorylated Antibodies > Phospho-Histone H2AX-S2 pAbBrand |
Leading Biology | Catalog Number |
AMR01030N |
Product Type |
Phosphorylated Antibodies | Field of Research |
Epigenetics & Nuclear Signaling>DNA Damage & Repair |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Phospho-Histone H2AX-S2 pAb.
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Molecular Weight |
Calculated MW:
15kDa
Observed MW:
Refer to figures
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Species Reactivity |
Rabbit
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Immunogen |
A phospho specific peptide corresponding to residues surrounding S2 of human H2AFX
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Cross Reactivity |
Human,Rat
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB
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Dilution |
WB 1:500 - 1:2000
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Product Description |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
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Synonyms |
H2AFX; H2A.X; H2A/X; H2AX; histone H2AX
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Images |
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Specification |
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Quantity |
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