> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Phosphorylated Antibodies > Phospho-Ret-Y905 pAbBrand |
Leading Biology | Catalog Number |
AMR01018N |
Product Type |
Phosphorylated Antibodies | Field of Research |
Cell Biology & Developmental Biology>Growth factors |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Phospho-Ret-Y905 pAb.
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Molecular Weight |
Calculated MW:
119kDa/124kDa
Observed MW:
124kDa
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Species Reactivity |
Rabbit
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Immunogen |
A synthetic phosphorylated peptide around Y905 of human Ret (NP_066124.1).
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Cross Reactivity |
Human
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB
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Dilution |
WB 1:500 - 1:2000
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Product Description |
This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed.
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Synonyms |
RET; CDHF12; CDHR16; HSCR1; MEN2A; MEN2B; MTC1; PTC; RET-ELE1; RET51; ret proto-oncogene
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Images |
Western blot analysis of extracts of K562 cells, using Phospho-Ret-Y905 antibody. |
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Specification |
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Quantity |
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Tel: 1-661-524(LBI)-0262
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