> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Phosphorylated Antibodies > Phospho-PDGFRA-Y754 pAbBrand |
Leading Biology | Catalog Number |
AMR00997N |
Product Type |
Phosphorylated Antibodies | Field of Research |
Cardiovascular>Angiogenesis |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Phospho-PDGFRA-Y754 pAb.
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Molecular Weight |
Calculated MW:
24kDa/82kDa/122kDa
Observed MW:
180kDa
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Species Reactivity |
Rabbit
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Immunogen |
A synthetic phosphorylated peptide around Y754 of human PDGFRA (NP_006197.1).
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Cross Reactivity |
Human
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB
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Dilution |
WB 1:500 - 1:2000
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Product Description |
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
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Synonyms |
PDGFRA; CD140A; PDGFR-2; PDGFR2; GAS9; RHEPDGFRA; platelet-derived growth factor receptor alpha
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Images |
Western blot analysis of extracts of HepG2 cells, using Phospho-PDGFRA-Y754 antibody. |
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Specification |
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Quantity |
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