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Phospho-P70 S6K-T389 pAb

Catalog # Availability Size / Price Inquiry
AMR00994N-1 50ul / $395
AMR00994N-2 100ul / $495
AMR00994N-3 200ul / $595

Phospho-P70 S6K-T389 pAb

Brand

Leading Biology

Catalog Number

AMR00994N

Product Type

Phosphorylated Antibodies

Field of Research

Endocrine & Metabolism>AMPK Signaling Pathway

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-P70 S6K-T389 pAb.

Molecular Weight

Calculated MW: 51kDa/52kDa/56kDa/59kDa Observed MW: 70kDa

Species Reactivity

Rabbit

Immunogen

A phospho specific peptide corresponding to residues surrounding T389 of human P70 S6K

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Product Description

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.

Synonyms

RPS6KB1; PS6K; S6K; S6K-beta-1; S6K1; STK14A; p70 S6KA; p70(S6K)-alpha; p70-S6K; p70-alpha; p70S6KA; ribosomal protein S6 kinase B1

Images

Western blot analysis of extracts of NIH/3T3 cells, using Phospho-P70 S6K-T389 antibody.

Immunohistochemistry of paraffin-embedded mouse heart using Phospho-P70 S6K-T389 antibody.

Immunohistochemistry of paraffin-embedded mouse kidney using Phospho-P70 S6K-T389 antibody.

Specification

Quantity

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