> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Phosphorylated Antibodies > Phospho-PRKACA-S339 pAbBrand |
Leading Biology | Catalog Number |
AMR00990N |
Product Type |
Phosphorylated Antibodies | Field of Research |
Endocrine & Metabolism>AMPK Signaling Pathway |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Phospho-PRKACA-S339 pAb.
|
||
Molecular Weight |
Calculated MW:
39kDa/40kDa
Observed MW:
42kDa
|
||
Species Reactivity |
Rabbit
|
||
Immunogen |
A synthetic phosphorylated peptide around S339 of human PRKACA (NP_002721.1).
|
||
Cross Reactivity |
Human
|
||
Isotype |
IgG
|
||
GeneID |
|||
UniProt ID |
|||
Purity |
Affinity purification |
||
Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
||
Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
|
||
Applications |
WB,IP
|
||
Dilution |
WB 1:500 - 1:2000
IP 1:50 - 1:100
|
||
Product Description |
This gene encodes one of the catalytic subunits of protein kinase A, which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits, in its inactive form. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. cAMP-dependent phosphorylation of proteins by protein kinase A is important to many cellular processes, including differentiation, proliferation, and apoptosis. Constitutive activation of this gene caused either by somatic mutations, or genomic duplications of regions that include this gene, have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing's syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. Tissue-specific isoforms that differ at the N-terminus have been described, and these isoforms may differ in the post-translational modifications that occur at the N-terminus of some isoforms.
|
||
Synonyms |
PRKACA; PKACA; PPNAD4; cAMP-dependent protein kinase catalytic subunit alpha
|
||
Images |
|
||
Specification |
|||
Quantity |
|
||
| Select | Brand | Catalog No. | Product Name | Pack Size | Type | Field of Research | Specification | Quantity | Price(USD) | |
| 1 | Leading Biology | AMR00900N | Phospho-CREB1-S133 pAb | 100ul | Phosphorylated Antibodies | Cell Biology & Developmental Biology>Apoptosis |
|
$495.00 | Add Ask | |
| 2 | Leading Biology | AMR01102N | Phospho-EGFR-Y1086 pAb | 100ul | Phosphorylated Antibodies | Cardiovascular>Angiogenesis |
|
$495.00 | Add Ask | |
| 3 | Leading Biology | AMR01066N | Phospho-FLNA-S2152 pAb | 100ul | Phosphorylated Antibodies | Cell Biology & Developmental Biology>Cytoskeleton |
|
$495.00 | Add Ask | |
| 4 | Leading Biology | AMR01229N | Phospho-PDGFRB-Y771 pAb | 100ul | Phosphorylated Antibodies | Cardiovascular>Angiogenesis |
|
$495.00 | Add Ask | |
| 5 | Leading Biology | APG03384N | Phospho-Histone H2A-S129 pAb | 100ul | Phosphorylated Antibodies |
|
$495.00 | Add Ask | ||
| 6 | Leading Biology | AMR01103N | Phospho-DPYSL2-T514 pAb | 100ul | Phosphorylated Antibodies | Neuroscience>Neurodegenerative Diseases |
|
$495.00 | Add Ask |
Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
You have 0 item in your cart
You have 0 item in your inquiry list
