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Phospho-PDGFR beta-Y751 pAb

Catalog # Availability Size / Price Inquiry
AMR00941N-1 50ul / $395
AMR00941N-2 100ul / $495
AMR00941N-3 200ul / $595

Phospho-PDGFR beta-Y751 pAb

Brand

Leading Biology

Catalog Number

AMR00941N

Product Type

Phosphorylated Antibodies

Field of Research

Cardiovascular>Angiogenesis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-PDGFR beta-Y751 pAb.

Molecular Weight

Calculated MW: 37kDa/123kDa Observed MW: 190kDa

Species Reactivity

Rabbit

Immunogen

A synthetic phosphorylated peptide around Y751 of human PDGFR beta (NP_002600.1).

Cross Reactivity

Human,Mouse

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB

Dilution

WB 1:500 - 1:2000

Product Description

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.

Synonyms

PDGFRB; CD140B; IBGC4; IMF1; JTK12; KOGS; PDGFR; PDGFR-1; PDGFR1; PENTT; platelet-derived growth factor receptor beta

Images

Western blot analysis of extracts of NIH/3T3 cells, using Phospho-PDGFR beta-Y751 antibody.

Specification

Quantity

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