> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Phosphorylated Antibodies > Phospho-STAT6-Y641 pAbBrand |
Leading Biology | Catalog Number |
AMR00920N |
Product Type |
Phosphorylated Antibodies | Field of Research |
Immunology & Inflammation>Jak-Stat-IL-6 Receptor Signaling Pathway |
Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Phospho-STAT6-Y641 pAb.
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Molecular Weight |
Calculated MW:
74kDa/81kDa/94kDa
Observed MW:
110kDa
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Species Reactivity |
Rabbit
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Immunogen |
A phospho specific peptide corresponding to residues surrounding Y641 of human STAT6
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Cross Reactivity |
Human
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Isotype |
IgG
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GeneID |
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UniProt ID |
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Purity |
Affinity purification |
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Storage Buffer |
Buffer: PBS with 50% glycerol, pH7.3.
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Applications |
WB
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Dilution |
WB 1:500 - 1:2000
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Product Description |
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.
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Synonyms |
STAT6; D12S1644; IL-4-STAT; STAT6B; STAT6C; signal transducer and activator of transcription 6
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Images |
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Specification |
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Quantity |
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2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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