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Phospho-SRC Family-Y416 pAb

Catalog # Availability Size / Price Inquiry
AMR00918N-1 50ul / $395
AMR00918N-2 100ul / $495
AMR00918N-3 200ul / $595

Phospho-SRC Family-Y416 pAb

Brand

Leading Biology

Catalog Number

AMR00918N

Product Type

Phosphorylated Antibodies

Field of Research

Cardiovascular>Angiogenesis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-SRC Family-Y416 pAb.

Molecular Weight

Calculated MW: 59kDa/60kDa Observed MW: 60kDa

Species Reactivity

Rabbit

Immunogen

A phospho specific peptide corresponding to residues surrounding Y416 of human SRC Family

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100

Product Description

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

Synonyms

SRC; ASV; SRC1; THC6; c-SRC; p60-Src; proto-oncogene tyrosine-protein kinase Src

Images

Western blot analysis of extracts from COLO205 cells, using Phospho-SRC Family-Y416 antibody.

Immunohistochemistry of paraffin-embedded human breast carcinoma tissue, using Phospho-SRC-Y416 antibody.

Specification

Quantity

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