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Phospho-NFkB p100-S866 pAb

Catalog # Availability Size / Price Inquiry
AMR00911N-1 50ul / $395
AMR00911N-2 100ul / $495
AMR00911N-3 200ul / $595

Phospho-NFkB p100-S866 pAb

Brand

Leading Biology

Catalog Number

AMR00911N

Product Type

Phosphorylated Antibodies

Field of Research

Cell Biology & Developmental Biology>Apoptosis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-NFkB p100-S866 pAb.

Molecular Weight

Calculated MW: 47kDa/96kDa Observed MW: 120kDa

Species Reactivity

Rabbit

Immunogen

A phospho specific peptide corresponding to residues surrounding S866 of human NFkB p100

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100

Product Description

This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.

Synonyms

NFKB2; CVID10; H2TF1; LYT-10; LYT10; NF-kB2; p100; p49/p100; p52; nuclear factor kappa B subunit 2

Images

Western blot analysis of extracts of MDA-MB435 cells, using Phospho-NFkB p100-S866 antibody.

Immunohistochemistry of paraffin-embedded human breast carcinoma using Phospho-NFkB p100-S866 antibody.

Immunofluorescence analysis of methanol-fixed HeLa cells using Phospho-NFkB p100-S866 antibody.

Specification

Quantity

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