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Phospho-VEGF Receptor 2-Y1175 pAb

Catalog # Availability Size / Price Inquiry
AMR00909N-1 50ul / $395
AMR00909N-2 100ul / $495
AMR00909N-3 200ul / $595

Phospho-VEGF Receptor 2-Y1175 pAb

Brand

Leading Biology

Catalog Number

AMR00909N

Product Type

Phosphorylated Antibodies

Field of Research

Cardiovascular>Angiogenesis

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-VEGF Receptor 2-Y1175 pAb.

Molecular Weight

Calculated MW: 75kDa/79kDa/151kDa Observed MW: 250kDa

Species Reactivity

Rabbit

Immunogen

A phospho specific peptide corresponding to residues surrounding Y1175 of human VEGF Receptor 2

Cross Reactivity

Human,Mouse,Rat

Isotype

IgG

GeneID

UniProt ID

Purity

Affinity purification

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Storage Buffer

Buffer: PBS with 50% glycerol, pH7.3.

Applications

WB,IHC,IF

Dilution

WB 1:500 - 1:1000 IHC 1:50 - 1:100 IF 1:100 - 1:200

Product Description

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.

Synonyms

KDR; CD309; FLK1; VEGFR; VEGFR2; kinase insert domain receptor

Images

Western blot analysis of extracts of HUVE cells, using Phospho-VEGF Receptor 2-Y1175 antibody.

Immunohistochemistry of paraffin-embedded human breast carcinoma using Phospho-VEGF Receptor 2-Y1175 antibody.

Immunofluorescence analysis of methanol-fixed MCF-7 cells using Phospho-VEGF Receptor 2-Y1175 antibody.

Specification

Quantity

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